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KMID : 1100220050040020104
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Dementia and Neurocognitive Disorders
2005 Volume.4 No. 2 p.104 ~ p.107
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Neuropsychological and Neuroimaging Findings in Two Cases of Capsular Genu Infarction
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Kim Jung-Eun
Kim Jae-Guk
Shin Hae-Eun
Kim Tae-Hyung
Lee Soo-Joo
Kim Sang-Yun
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Abstract
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An internal capsule genu infarct has been infrequently reported to cause cognitive impairment and behavioral changes. We report two previously non-demented patients who developed amnesia and bulbo-facial weakness. Neuropsychological findings showed prominent multiple cognitive dysfunctions and brain perfusion SPECT demonstrated hypoperfusion in the bilateral fronto-temporal cortex, ipsilateral thalamus and occipital cortex and controlateral cerebellar cortex. These findings suggest a disconnection or diaschisis of thalamo-cortical interconnection as the possible mechanism explaining the development of cognitive dysfunction after capsular genu infarction.
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KEYWORD
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Internal capsule genu, Cognitive dysfunction, Brain perfusion SPECT
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